Best medicine for Anal Fissure in Ayurvedic Treatment. Anal Fissure Treatment 1. ABHAYARISHTA (Oral Syrup) IMPCOPS (Brand) Dosage 15-30 ml twice daily, 2. Jatya d i Taila (Oil) Dhanvantari Herbs (Brand) Topical Application with cotton on the Anal Fissure, 3. KAILAS JEEVAN (Multipurpose Ayurvedic Cream) Topical Application on the Anal Fissure, I have used Resperidon a medicine for mental disorder which caused severe constipation and that prolonged constipation has lead to single Anal fissure in my case. First and fore most cure for my Anul Fissure is slowly i changed my diet to rich in fiber and low corb diet contains vegitables and fruits. Avoid chillies and processed food. Take more buttermilk, sabja seeds juice, lemon and barley water. I totally suffered from Anal Fissure for nearly 2 months with severe pain during defecation and lot of pain in carrying my routine job unable to sit, i changed 2 to 3 medications in ayurveda but no use, later